Low sperm morphology and miscarriage

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This measures many features of the sperm and semen the fluid in which the sperm are contained. The most important of these are the number of sperm sperm countmotility of the sperm percentage of moving spermmorphology of the sperm percentage of normally shaped spermand the volume of fluid. To assess sperm morphology, the sperm are examined under a microscope and the percentage of abnormally shaped sperm is estimated.

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Even if a patient has successfully conceived but has then experienced a miscarriage, it may be a condition within the male partner that is causing the pregnancy complications. The count and shape of the sperm should be tested for and can reveal the actual issue that requires treatment. In many cases of abnormal sperm shape or morphologythere is defective or fragmented DNA which can lead to pregnancy but abnormal development and loss of the embryo.

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Sperm morphology — the size and shape of sperm — is one factor that's examined as part of a semen analysis to evaluate male infertility. Sperm morphology results are reported as the percentage of sperm that appear normal when semen is viewed under a microscope. Normal sperm have an oval head with a long tail.

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Sperm morphology is the best predictor of fertilization potential, and the critical predictive information for supporting assisted reproductive methods selection. This is an open-access article distributed under the terms of the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability: The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper and its Supporting Information files.

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NEW ORLEANS — Men with lower rates of normal sperm morphology and weakened sperm motility, as well as higher levels of seminal reactive oxygen species and DNA fragmentation index, were more likely to have partners with three consecutive pregnancy losses before reaching 20 weeks of gestation, according to findings presented at the Endocrine Society Annual Meeting. The findings are based on comparisons of the sperm of 49 men whose partners experienced multiple pregnancy losses vs. More on his findings can be found by clicking here.

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Multiple miscarriages may be linked to the poor quality of a man's sperm, suggests new research. The early-stage study, from scientists at Imperial College London, investigated the sperm quality of 50 men whose partners had suffered three or more consecutive miscarriages. The research, published in the journal Clinical Chemistryrevealed that, compared to men whose partners had not experienced miscarriages, the sperm of those involved in the study had higher levels of DNA damage.

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Around a quarter of all couples will experience a miscarriage. High levels of sperm DNA fragmentation have been shown to double the likelihood of a miscarriage occurring. Around a quarter of all couples will experience the heartache of miscarriage at some time.

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But a small government-funded study by scientists at Imperial College London suggests miscarriage could also be a result of male issues, particularly if they are not routinely tested. For instance, previous research suggests sperm has an important role in the formation of the placenta, which is crucial for oxygen and nutrient supply to the foetus. The scientists analysed their sperm and compared the results with those of 60 similar male volunteers. The sperm of the men in the miscarriage group had twice as much DNA damage as that in the control group, they found.

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Never miss a great news story! Get instant notifications from Economic Times Allow Not now. Pregnant women should avoid night shifts; it increases risk of miscarriage.

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